Fully automated dual-color dual-hapten silver in situ hybridization staining for MYC amplification: a diagnostic tool for discriminating secondary angiosarcoma.
Identifieur interne : 002A70 ( Main/Exploration ); précédent : 002A69; suivant : 002A71Fully automated dual-color dual-hapten silver in situ hybridization staining for MYC amplification: a diagnostic tool for discriminating secondary angiosarcoma.
Auteurs : Jennifer S. Ko [États-Unis] ; Steven D. Billings ; Christopher P. Lanigan ; Darya Buehler ; Anthony P. Fernandez ; Raymond R. TubbsSource :
- Journal of cutaneous pathology [ 1600-0560 ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Amplification de gène, Argent (), Femelle, Humains, Hybridation in situ (), Hémangiosarcome (anatomopathologie), Hémangiosarcome (génétique), Hémangiosarcome (métabolisme), Mâle, Protéines proto-oncogènes c-myc (génétique), Protéines proto-oncogènes c-myc (métabolisme), Sujet âgé, Sujet âgé de 80 ans ou plus, Tumeurs cutanées (anatomopathologie), Tumeurs cutanées (génétique), Tumeurs cutanées (métabolisme), Tumeurs radio-induites (anatomopathologie), Tumeurs radio-induites (génétique), Tumeurs radio-induites (métabolisme), Études rétrospectives.
- MESH :
- anatomopathologie : Hémangiosarcome, Tumeurs cutanées, Tumeurs radio-induites.
- génétique : Hémangiosarcome, Protéines proto-oncogènes c-myc, Tumeurs cutanées, Tumeurs radio-induites.
- métabolisme : Hémangiosarcome, Protéines proto-oncogènes c-myc, Tumeurs cutanées, Tumeurs radio-induites.
- Adulte, Adulte d'âge moyen, Amplification de gène, Argent, Femelle, Humains, Hybridation in situ, Mâle, Sujet âgé, Sujet âgé de 80 ans ou plus, Études rétrospectives.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Female, Gene Amplification, Hemangiosarcoma (genetics), Hemangiosarcoma (metabolism), Hemangiosarcoma (pathology), Humans, In Situ Hybridization (methods), Male, Middle Aged, Neoplasms, Radiation-Induced (genetics), Neoplasms, Radiation-Induced (metabolism), Neoplasms, Radiation-Induced (pathology), Proto-Oncogene Proteins c-myc (genetics), Proto-Oncogene Proteins c-myc (metabolism), Retrospective Studies, Silver (chemistry), Skin Neoplasms (genetics), Skin Neoplasms (metabolism), Skin Neoplasms (pathology).
- MESH :
- chemical , chemistry : Silver.
- chemical , genetics : Proto-Oncogene Proteins c-myc.
- genetics : Hemangiosarcoma, Neoplasms, Radiation-Induced, Skin Neoplasms.
- metabolism : Hemangiosarcoma, Neoplasms, Radiation-Induced, Proto-Oncogene Proteins c-myc, Skin Neoplasms.
- methods : In Situ Hybridization.
- pathology : Hemangiosarcoma, Neoplasms, Radiation-Induced, Skin Neoplasms.
- Adult, Aged, Aged, 80 and over, Female, Gene Amplification, Humans, Male, Middle Aged, Retrospective Studies.
Abstract
MYC amplification occurs in post-radiation and chronic lymphedema-associated secondary angiosarcoma and some primary angiosarcomas. In this study, we tested the ability of automated dual-color dual-hapten in situ hybridization (DISH) staining to discriminate secondary angiosarcoma from radiation-associated atypical vascular lesions (AVL), and to correlate with fluorescence in situ hybridization (FISH) for MYC amplification.
DOI: 10.1111/cup.12278
PubMed: 24329959
Affiliations:
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Le document en format XML
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<term>Hemangiosarcoma (metabolism)</term>
<term>Hemangiosarcoma (pathology)</term>
<term>Humans</term>
<term>In Situ Hybridization (methods)</term>
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<term>Middle Aged</term>
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<term>Neoplasms, Radiation-Induced (metabolism)</term>
<term>Neoplasms, Radiation-Induced (pathology)</term>
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<front><div type="abstract" xml:lang="en">MYC amplification occurs in post-radiation and chronic lymphedema-associated secondary angiosarcoma and some primary angiosarcomas. In this study, we tested the ability of automated dual-color dual-hapten in situ hybridization (DISH) staining to discriminate secondary angiosarcoma from radiation-associated atypical vascular lesions (AVL), and to correlate with fluorescence in situ hybridization (FISH) for MYC amplification.</div>
</front>
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<region><li>Ohio</li>
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<name sortKey="Buehler, Darya" sort="Buehler, Darya" uniqKey="Buehler D" first="Darya" last="Buehler">Darya Buehler</name>
<name sortKey="Fernandez, Anthony P" sort="Fernandez, Anthony P" uniqKey="Fernandez A" first="Anthony P" last="Fernandez">Anthony P. Fernandez</name>
<name sortKey="Lanigan, Christopher P" sort="Lanigan, Christopher P" uniqKey="Lanigan C" first="Christopher P" last="Lanigan">Christopher P. Lanigan</name>
<name sortKey="Tubbs, Raymond R" sort="Tubbs, Raymond R" uniqKey="Tubbs R" first="Raymond R" last="Tubbs">Raymond R. Tubbs</name>
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<country name="États-Unis"><region name="Ohio"><name sortKey="Ko, Jennifer S" sort="Ko, Jennifer S" uniqKey="Ko J" first="Jennifer S" last="Ko">Jennifer S. Ko</name>
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